Painkillers make antidepressants less effective, study shows

Commonly used painkillers such as ibuprofen and acetylsalicylic acid can undermine the effectiveness of antidepressants, new research suggests. The study, published on Tuesday in the medical journal Proceedings of the National Academy of Sciences, examined the interaction between antidepressants such as Zoloft, Paxil or Prozac and painkillers like Aspirin and Advil.

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